标题:Effect of Inhibin α(1-32)Gene Immunization on the Follicular Development and Reproductive Hormones i

作者:

摘要:<正&gt; A total of 40 rats, aged in 30 days. were divided into 4 groups and immunized (intramuscularly injection) with 0 μg(control), 15μg (group 1), 25μg (group 2) or 40 μg (group 3) of inhibin α(1-32) re-combinant expression plasmid pcINH in combination with liposome. Booster was given without liposome on day 20 after primary immunization. The results showed that 50%(13/26) rats were detected in positive antibody against inhibin. However, the increase of immunization dosage and booster did not promote the ratio of antibody positive rats. The number of matured follicles above 0.8 mm in diameter in the antibody positive rats was 2.3 more than that in the negative rats (P>0. 05). The concentration of blood plasma FSH increased distinctively on day 10 after primary immunization (P<0. 05), but no increase was observed after booster immunization. The 17-β-estradiol levels in blood plasma of rats between the positive and the negative groups had no remarkable differences (P>0.05). These results suggested that r

关键词:Inhibin gene;Immunization;Follicular development;

文献注录:. Effect of Inhibin α(1-32)Gene Immunization on the Follicular Development and Reproductive Hormones i [J]. Agricultural Sciences in China. 2003, 03: 105-111.

报/刊名:Agricultural Sciences in China》,发表于2003 / 第 03 期。

文献类型: [J] (文献级别:核心刊物

页码: 105-111 页 / 共7

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